Can I Take my Prescriptions While on the Cleanse?

This is a Frequently Asked Question that I don’t yet have a great answer for. If you have an opinion, please post a comment or email. To err on the cautious side, I would continue to take my prescriptions until I had consulted with my doctor, just to ensure there are no problems due to either a lack of nutrition or the addition of something unwelcome from the Master Cleanse ingredients themselves.

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  1. Ekho August 7, 2015 at 9:44 pm #

    Hi all,

    I know that this can be a grave concern for many of you, so I’ve done my research by surfing the net, speaking with doctors, and a few “trial and error” routines of my own.
    Here’s how this works:

    The Master Cleanse is designed to partially stint your metabolism so that you are requiring less and less food as time goes on, therefore you eat less and/or better.
    Weight loss is a side effect! Weight loss has never been the primary goal for this routine, it’s just a perk or “side effect”.
    Well, because of your digestive tract being slowed near a halt, you can’t eat anything – that defeats the purpose. Pills have to be digested so that they are broken down to access your bloodstream, therefore pills cannot be taken… WHOLE. Many people recommend liquid capsules, but oftentimes your body still has to break down the capsule. SO. If you have a prescription medication that NEEDS to be taken, it needs to be crushed to a fine powder and mixed with a drink from that particular hour of the day. Prescriptions that are required to be taken with food will need a little boost. The recommended solution is to take a men’s or women’s multi-vitamin (crushed, of course) at least forty-five minutes prior to taking your powdered medication, so that your body is tricked into thinking it has had solid nutrients.
    The multi-vitamins – or prenatal vitamins – are also good for making the entire detox easier, day by day.
    Additionally, if you have an iron deficiency like myself, the crushed vitamins provide just as much help as they did before the detox and will not harm the detoxing process at all.

    Best of luck and happy cleansing to all,

    • Difranco August 15, 2015 at 6:50 am #

      What is your opinion of prescription pain meds/opioids in this regard? When taken on a long-term daily basis, the body becomes/may become physically dependent, and I wonder if one may experience medication detox/withdrawal symptoms on the cleanse. If the medication does not absorb properly in the system, or if it is eliminated too quickly, this could potentially be a problem. Does the digestion process slow during the cleanse, or does it start working more efficiently? Something as simple as drinking too much apple juice (resulting in a laxative effect) can reduce the time these medications remain in the body, creating a painful drug withdrawal situation. I really wonder about this.

      In my personal case, I am in the process of weaning off of my pain medication (thank God I have had no problems thus far), and I am seriously concerned about losing my progress– or starting the cleanse, getting “sick”, and then having to abandon my fast. Anybody have experience with any of this? I am double-minded about it- I am thinking it could possibly help the drug detox symptoms disappear more quickly (thus making it easier to wean off); and I am also thinking it could detox the body so well, that the drug withdrawal symptoms would become unbearable. I would hate to begin a negative relationship with fasting. I assume that waiting to cleanse until I am completely off the meds would be the safest route, but I am really not sure. What does anybody think about this? Any insights would be appreciated :D Thanks!

  2. ERiCA January 12, 2015 at 9:54 am #

    What do you think about taking anti-depressants and mood stabilizers during the cleanse…?

  3. TC October 31, 2014 at 10:20 pm #

    I have the same question: I can have a seizure and can die due to my brain tumour if I don’t take my meds. My main concern is that my medication is hard on the stomach lining (can deteriorate it) and “has to be taken with food or milk” as per the pharmaceutical instructions. Can I still due this diet?

    I have done this cleanse once before and continued to take my pills during the cleanse (and I was amazed at the results, with no stomach/stomach lining issues in 10 years to speak of), but that doesn’t mean I should do it again. So whad’ya say?

    Anyone else tried it during/with their meds?

  4. Holly January 5, 2013 at 9:07 am #

    If you are taking regular medications, first of all, you should know everything about those medications including how they work, how they are absorbed, their contraindications, side effects, etc. Then, absolutely do not do this cleanse program (or any other cleanse program) before checking with your doctor telling her/him exactly what your cleanse program consists of and what medications you are on. This is just common sense.

  5. Aubrey June 4, 2012 at 11:30 pm #

    I strongly disagree with the other poster who suggests NOT taking prescriptions without a doctor’s permission. For purposes of those “take with food” medicines, many are so that the patient doesn’t experience stomach pain from the harshness of the medication, and the lemonade diet would suffice for that purpose. I can’t think of many ideas that are so obviously unwise as not taking a prescription medication for a medical condition you have without asking your doctor. Internet forums are no substitute for medical judgment from someone who actually knows you personally. If you have a condition requiring medication and you think The Master Cleanse might adversely impact that medication, you should probably wait to start the cleanse. There are many other more gentle cleanses out there that can probably still help you with your cleansing goals.

  6. Hannah Brooks July 28, 2011 at 9:42 am #

    My suggestion: if you are on prescription medication ask your doctor first.
    Many medications must be taken with food in order to enter the body properly.

    I would say NO not without the doctor’s permission

  7. Megan April 17, 2011 at 12:17 pm # has some great links about specific aliments/medications. I looked at this with my own issue. I have Hasimotos (a thyroid dysfunction similar to hypothyroidism). This website is not specific the the Master Cleanse; it does however touch on some interesting topics, like juicing.

    Because of what it said on here I am continuing to take my thyroid medication (I am on day 2 currently of my 1st cleanse ever!). I would also assume diabetics and others with autoimmune diseases would be better to maintain their dosage until they speak with a doctor. You should always have your levels checked frequently as it is. I intend to have my levels checked within the month when I complete the MC; taking too much of your medication when your levels change is just as bad as not enough.

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